Chronic Osteomyelitis
Mid-to-Long-Term Results of Single-stage Surgery for Patients with Chronic Osteomyelitis Using a Bio Absorbable Gentamicin-loaded Ceramic Carrier
Authors: McNally et al.
Publication: The Bone & Joint Journal (2022)
Summary: Patients with chronic osteomyelitis, treated by surgery, implantation of CERAMENT® G and systemic antibiotics, followed up for an average of 6.05 years.
RESULTS:
- 100 patients
- 94% infection eradication in a single-stage surgery
- 3% fracture rate (71 patients out of 100 were FRI patients)
Radiographic and Histological Analysis of a Synthetic Bone Graft Substitute Eluting Gentamicin in the Treatment of Chronic Osteomyelitis
Authors: Ferguson et al.
Publication: The Journal of Bone and Joint Infection (2019)
Summary: Patients with chronic osteomyelitis, treated by surgery, implantation of CERAMENT® G, and systemic antibiotics. 138 of these patients had minimum one-year radiographic follow-up (mean 1.7 yrs). 9 patients had subsequent surgery that allowed for histology of biopsies between 19 days-2 years after implantation of CERAMENT® G. Histology “confirmed active remodeling of [CERAMENT® G] into osteoid and lamellar bone”
RESULTS:
- 163 patients
- 2.5% fracture rate
- 73.8% mean void filling
- 95.7% infection eradication