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Fracture Related Infection

Up to 30% of fractures become infected (Baertl et al. 2021)​ and despite advances in treatment 62% of patients have 2 or 3 surgeries (Bezstarosti et al.  2019) and the failure rate following surgery is reported to be between 13-39% (Obremskey et al. 2017, Yong et al. 2022 and McNally et al. 2022).

Whether retaining or removing metalwork in a fracture-related infection, CERAMENT G offers a user and patient-friendly solution for managing dead space, with proven results. Please have a look at our materials below on how to use antibiotic-eluting CERAMENT for best outcomes, example cases and clinical results.

Intramedullary Nailing with an Absorbable Antibiotic Carrier (Inaac): A Simple Technique Using Standard Implants

Authors: Pomeroy et al.
Publication: Journal of Orthopaedic Science and Research (2024)
Summary: This paper reports a simple technique for coating an intramedullary nail with an absorbable antibiotic carrier.
RESULTS:
  • 3% infection free (21/23 patients)
  • 7% achieved union (18/21patients)
  • No complications related to technique
Read the Full Study

Augmented Debridement for Implant-Related Chronic Osteomyelitis with an Absorbable, Gentamicin Loaded Calcium Sulfate/Hydroxyapatite Biocomposite

Authors: Drampalos et al.
Publication: The Journal of Orthopaedics (2020)
Summary: Patients with implant related chronic osteomyelitis, treated by removal of metalwork, debridement and augmentation with CERAMENT® G and systemic antibiotics. Mean follow-up was 17 months.
RESULTS:
  • 52 Patients
  • No Fractures
  • 92.3% infection eradication
  • 81.9% infected non-unions healed
  • “Bone remodeling in all patients”
Read the Full Study

Treatment of Fracture-Related Infection of the Lower Extremity with Antibiotic-Eluting Ceramic Bone Substitutes: Case Series of 35 Patients and Literature Review.

Authors: Pesch et al.
Publication: Infection (2020)
Summary: Patients with fracture-related infections treated in either a single – or two stage debridement and implantation of CERAMENT® G, followed up for a mean of 14.9 months.
RESULTS:
  • 35 patients
  • No fractures
  • 91.4% infection eradication
Read the Full Study

Hear From the Experts

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Research & Related Videos

cover Podcast Bone Infection Management

Bone Infection Management Tools You Should Know

Scott M. Sandilands, DO moderates a conversation about the uses of CERAMENT G in open fractures and fracture-related infections with Peter Everson, MD and Augustine Saiz, MD.

The conversation highlights the 2-CAN technique for IM nailing, where CERAMENT G is delivered alongside intramedullary fixation to provide both structural stability and targeted local antibiotic delivery.

cover Podcast New Tool for Infection Mgmt

A New Tool for Infection Management

Stephen Quinnan, MD moderates a conversation about the uses of CERAMENT G in open fractures and fracture-related infections with Charles N. Moon, MD and Scott M. Sandilands, DO. In it, they not only discuss the clinical evidence supporting their practices, but benefits of single stage procedures, bone remodeling, and infection management.

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